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Mcclain, Donald

One or more keywords matched the following items that are connected to Mcclain, Donald

Item Type	Name
Concept	Insulin Resistance
Academic Article	Early mitochondrial adaptations in skeletal muscle to diet-induced obesity are strain dependent and determine oxidative stress and energy expenditure but not insulin sensitivity.
Academic Article	Activation of the hexosamine signaling pathway in adipose tissue results in decreased serum adiponectin and skeletal muscle insulin resistance.
Academic Article	MitoNEET-driven alterations in adipocyte mitochondrial activity reveal a crucial adaptive process that preserves insulin sensitivity in obesity.
Academic Article	Adipocyte iron regulates adiponectin and insulin sensitivity.
Academic Article	Cardiac expression of kinase-deficient 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase inhibits glycolysis, promotes hypertrophy, impairs myocyte function, and reduces insulin sensitivity.
Academic Article	Adipocytes with increased hexosamine flux exhibit insulin resistance, increased glucose uptake, and increased synthesis and storage of lipid.
Academic Article	Iron and diabetes risk.
Academic Article	Dietary iron restriction or iron chelation protects from diabetes and loss of beta-cell function in the obese (ob/ob lep-/-) mouse.
Academic Article	Increased strength and physical performance with eccentric training in women with impaired glucose tolerance: a pilot study.
Academic Article	Contribution of insulin and Akt1 signaling to endothelial nitric oxide synthase in the regulation of endothelial function and blood pressure.
Academic Article	Increased hexosamine pathway flux and high fat feeding are not additive in inducing insulin resistance: evidence for a shared pathway.
Academic Article	Hexosamines regulate sensitivity of glucose-stimulated insulin secretion in beta-cells.
Academic Article	Transgenic mice overexpressing the rate-limiting enzyme for hexosamine synthesis in skeletal muscle or adipose tissue exhibit total body insulin resistance.
Academic Article	Altered glycan-dependent signaling induces insulin resistance and hyperleptinemia.
Academic Article	Recipes for creating animal models of diabetic cardiovascular disease.
Academic Article	Insulin resistance of glycogen synthase mediated by o-linked N-acetylglucosamine.
Grant	Iron reduction by phlebotomy for the prevention and treatment of type 2 diabetes
Grant	Hexosamines, Glucose Toxicity and Insulin Resistance
Grant	DIABETES IN HEMOCHROMATOSIS: PREVALENCE AND MECHANISMS
Grant	Diabetes in Hemochromatosis: Prevalence and Mechanisms
Academic Article	Adipose Tissue Transferrin and Insulin Resistance.
Grant	Iron Reduction for the Treatment of Diabetes and Nonalcoholic Fatty Liver Disease
Academic Article	Effect of Chronic Hyperglycemia on Glucose Metabolism in Subjects With Normal Glucose Tolerance.
Academic Article	Low dose chloroquine decreases insulin resistance in human metabolic syndrome but does not reduce carotid intima-media thickness.
Grant	Mechanism of Integrative Metabolic Regulation by Iron and Hypoxia

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Insulin Resistance